Journal of Integrative Plant Biology, 60 (6) : 448-454, June 2018     Research Article

OPEN ACCESS ARTICLE

ANAPHASE PROMOTING COMPLEX/CYCLOSOME©\mediated cyclin B1 degradation is critical for cell cycle synchronization in syncytial endosperms[OA]

Lei Guo1, Li Jiang1†, Xiu-Li Lu1 and Chun-Ming Liu1,2
1Key Laboratory of Plant Molecular Physiology, Institute of Botany, Chinese Academy of Sciences, Beijing 100093, China
2Institute of Crop Sciences, Chinese Academy of Agricultural Sciences, Beijing 100081, China

Present address: Chinese Academy of Fishery Sciences, Beijing 100141, China

Correspondence:
Email: Chun-Ming Liu (cmliu@ibcas.ac.cn)

Online on 9 Feb 2018 at www.jipb.net and www.wileyonlinelibrary.com/journal/jipb

Abstract

Although it is known that in most angiosperms mitosis in early endosperm development is syncytial and synchronized, it is unclear how the synchronization is regulated. We showed previously that APC11, also named ZYG1, in Arabidopsis activates zygote division by interaction and degradation of cyclin B1. Here, we report that the mutation in APC11/ZYG1 led to unsynchronized mitosis and over©\accumulation of cyclin B1©\GUS in the endosperm. Mutations in two other APC subunits showed similar defects. Transgenic expression of stable cyclin B1 in the endosperm also caused unsynchronized mitosis. Further, downregulation of APC11 generated multi©\nucleate somatic cells with unsynchronized mitotic division. Together, our results suggest that APC/C©\mediated cyclin B1 degradation is critical for cell cycle synchronization.


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Received 17 Dec 2017   Accepted 6 Feb 2018
© 2017 Institute of Botany, Chinese Academy of Sciences


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