Abstract: In a search for structurally interesting substances from traditional Chinese medicines, eight compounds were isolated from an ethanolic extract of the stem bark of Daphne giraldii Nitsche. On the basis of one- and two-dimensional nuclear magnetic resonance and mass spectrometry data, and chemical methods, their structures were determined to be 2H-1-benzopyran-2-one-8-hydroxy-7-O--D-glucopyranosyl-5-(2-oxo-2H-1-benzopyran-7-hydroxy-8-yloxy) (compound 1), 1-pentanone, 1-(4-hydroxyphenyl)-5-phenyl (compound 2), octadecyl caffeate (compound 3), (+)syringaresinol-4,4''-diglycoside (compound 4), daphnetin-8-O--D-glucopyranoside (compound 5), p-hydroxybenzoic acid (compound 6), 7,7''-dihydroxy-[6, 8''-bi-2H-benzopyran]-2, 2''-dione (compound 7), and daphnorin (compound 8), respectively. Of the compounds isolated, compounds 1 and 2, which we named daphnolin and daphnolon, respectively, were new, and the others were obtained from this plant for the first time.(Author for correspondence. Tel: +86 (0)25 8539 1248; Fax: +86 (0)25 8531 1528; E-mail: njjjq@yahoo.com.cn)

Key words: Daphne giraldii, daphnolin, daphnolon, dicoumaringlycoside.