J Integr Plant Biol. ›› 1986, Vol. 28 ›› Issue (2): -.

• Research Articles •    

Studies on Diterpenoids ot Rabdosia macrocalyx var. jiuhua Z. W. Xue et X. W. Wang

Wang Zhao-quan, Wang Xian-rong, Dong Jin-guang and Wang Xue-wen   

Abstract: Four diterpenoids have been isolated from the dried leaves of Rabdosia macrocalyx var. juihua Z. W. Xue et X..W. Wang. Three of them were shown to be known diter- penoids, excisanin A, excisanin B and macrocalyxin A, while the one, a new kauranetype diterpene, was named jiuhuanin A. On the basis of physico-chemical constants, spectroscopic analysis of the new compound and properties of its derivatives, the structure of the compound was identified as (1). Jiuhuanin A was shown to have cytotoxicity in vitro against cultures of Hela cell and A549 cells.

Key words: Rabdosia macrocalyx var. juihua Z. W. Xue et X. W. wang, diter- penoid, Jiuhuanin A, Excisanin A, Excisanin B, Macrocalyxin A

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