Associate Professor Giovanna Serino

Dipartimento di Genetica e Biologia Molecolare
Universita La Sapienza
Piazzale Aldo Moro 5
00185 Rome
Italy
Tel: +39-06-49912922
E-mail: giovanna.serino@uniroma1.it
http://www.biotech-genom.uniroma1.it/cgi-bin/campusnet/docenti.pl/Show?_id=serino
Area of expertise: Ubiquitin ; proteasome; Arabidopsis thaliana; light signaling; protein degradation
Co-editor until: October 31, 2011

• Wei N, Serino G, Deng XW (2008) The COP9 signalosome: more than a protease. Trends Biochem. Sci. 33, 592-600.
• Gusmaroli G, Figueroa P, Serino G, Deng XW (2007) Role of the MPN subunits in COP9 signalosome assembly and activity, and their regulatory interaction with Arabidopsis Cullin3-based E3 ligases. Plant Cell 19, 564-581.
• Cecchetti V, Altamura MM, Serino G, Pomponi M, Falasca G, Costantino P, Cardarelli M (2007) ROX1, a gene induced by rolB, is involved in procambial cell proliferation and xylem differentiation in tobacco stamen.Plant J. 49, 27-37.
• Figueroa P, Gusmaroli G, Serino G, Habashi J, Ma L, Shen Y, Feng S, Bostick M, Callis J, Hellmann H, Deng XW (2005) Arabidopsis has two redundant Cullin3 proteins that are essential for embryo development and that interact with RBX1 and BTB proteins to form multisubunit E3 ubiquitin ligase complexes in vivo. Plant Cell 17, 1180-1195.
• Serino G, Deng XW (2003) The COP9 signalosome: regulating plant development through the control of proteolysis. Annu. Rev. Plant Biol. 54, 165-182.
• Serino G, Su H, Peng Z, Tsuge T, Wei N, Gu H, Deng XW (2003) Characterization of the last subunit of the Arabidopsis COP9 signalosome: implications for the overall structure and origin of the complex. Plant Cell 15, 719-731.
• Schwechheimer C, Serino G, Deng XW (2002) Multiple ubiquitin ligase-mediated processes require COP9 signalosome and AXR1 function. Plant Cell 14, 2553-2563.
• Liu Y, Schiff M, Serino G, Deng XW, Dinesh-Kumar SP (2002) Role of SCF ubiquitin-ligase and the COP9 signalosome in the N gene-mediated resistance response to Tobacco mosaic virus. Plant Cell 14, 1483-1496.
• Wang X, Kang D, Feng S, Serino G, Schwechheimer C, Wei N (2002) CSN1 N-terminal-dependent activity is required for Arabidopsis development but not for Rub1/Nedd8 deconjugation of cullins: a structure-function study of CSN1 subunit of COP9 signalosome. Mol. Biol. Cell 13, 646-655.