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Professor Johan Memelink

Institute of Biology
Leiden University
Sylviusweg 72
The Netherlands
Tel: +31-71-527-4751; Fax: +31-71-527-4999
E-mail: j.memelink@biology.leidenuniv.nl
http://biology.leidenuniv.nl/ibl/Organisation/OrganisationPeopleInfo.php?PeopleID=69
Area of expertise: Transcription factors; secondary metabolism (alkaloids); jasmonate signaling
Co-editor until: Dec. 31, 2010

   
Selected Publications:  
   
  • Leon-Reyes A, Du Y, Koornneef A, Proietti S, Körbes AP, Memelink J, Pieterse CM, Ritsema T (2010) Ethylene signaling renders the jasmonate response of Arabidopsis insensitive to future suppression by salicylic acid. Mol. Plant Microbe. Interact. 23, 187-197.
  • Maraschin Fdos S, Memelink J, Offringa R (2009) Auxin-induced, SCFTIR1-mediated poly-ubiquitination marks AUX/IAA proteins for degradation. Plant J. 59, 100-109.
  • Memelink J (2009) Regulation of gene expression by jasmonate hormones. Phytochemistry 70, 1560-1570.
  • Pré M, Atallah M, Champion A, De Vos M, Pieterse CM, Memelink J (2008) The AP2/ERF domain transcription factor ORA59 integrates jasmonic acid and ethylene signals in plant defense. Plant Physiol. 147, 1347-1357.
  • Costa MM, Hilliou F, Duarte P, Pereira LG, Almeida I, Leech M, Memelink J, Barceló AR, Sottomayor M (2008) Molecular cloning and characterization of a vacuolar class III peroxidase involved in the metabolism of anticancer alkaloids in Catharanthus roseus. Plant Physiol. 146, 403-417.
  • Memelink J (2005) The use of genetics to dissect plant secondary pathways. Curr. Opin. Plant Biol. 8, 1-6.
  • Memelink J (2005) Tailoring the plant metabolome without a loose stitch. Trends Plant Sci. 10, 305-307.
  • Atallah M, Memelink J (2004) Plant response to stress: role of the jasmonate signal transduction pathway. In: Encyclopedia of Plant and Crop Science, RM Goodman (ed.), Marcel Dekker Inc., New York , USA , pp. 1006-1009.
  • Memelink J (2004) Putting the opium in poppy to sleep. Nat. Biotechnol. 22, 1526-1527.
  • Pauw B, Hilliou FA, Martin VS, Chatel G, de Wolf CJ, Champion A, Pré M, van Duijn B, Kijne JW, van der Fits L, Memelink J (2004) Zinc finger proteins act as transcriptional repressors of alkaloid biosynthesis genes in Catharanthus roseus. J. Biol. Chem. 279, 52940-52948.
  • Pauw B, van Duijn B, Kijne JW, Memelink J (2004) Activation of the oxidative burst by yeast elicitor in Catharanthus roseus cells occurs independently of the activation of genes involved in alkaloid biosynthesis. Plant Mol. Biol. 55, 797-805.
  • Pauw B, Hilliou FA, Martin VS, Chatel G, de Wolf CJ, Champion A, Pré M, van Duijn B, Kijne JW, van der Fits L, Memelink J (2004) Zinc finger proteins act as transcriptional repressors of alkaloid biosynthesis genes in Catharanthus roseus. J. Biol. Chem. 279, 52940-52948.
  • Chatel G, Montiel G, Pré M, Memelink J, Thiersault M, Saint-Pierre B, Doireau P, Gantet P (2003) CrMYC1 , a Catharanthus roseus elicitor- and jasmonate-responsive bHLH transcription factor that binds the G-box element of the strictosidine synthase gene promoter. J. Exp. Bot. 54, 2587-2588.
  • Memelink J (2003) T-DNA Activation tagging. In: Methods in Molecular Biology, vol. 236: Plant Functional Genomics: Methods and Protocols. Ed: Grotewold E. Humana Press Inc, Totowa NJ , USA, pp. 343-359.
  • Twyman RM, Verpoorte R, Memelink J, Christou P (2003) Genetic modification of secondary metabolism: Alkaloids.  In: Thomas B, Murphy DJ, Murray B (eds) Encyclopedia of Applied Plant Sciences. Academic Press, NY, pp. 493-500.
  • Gantet P, Memelink J (2002) Transcription factors: tools to engineer production of pharmacologically active plant metabolites. Trends Pharmacol. Sci. 23, 563-569.
  • Verpoorte R , Contin A, Memelink J (2002) Biotechnology for the production of plant secondary metabolites. Phytochemistry Rev. 1, 13-25.
  • Verpoorte R , Ingkaninan K, Memelink J , van der Heijden R (2002) New perspectives for plant secondary metabolite production. In: Natural Products in the New Millennium - Prospects and Industrial Application, Proceedings Phytochemical Society of Europe Vol. 47, Eds. A.P. Rauter, F.B. Palma, J.Justino, M.E.A.Araujo, S.P.dos Santos, Kluwer Academic Publishers, Dordrecht, pp. 345-366.
  • Verpoorte R, Memelink J (2002) Engineering secondary metabolite production in plants. Curr. Opin. Biotechnol. 13, 181-187.
  • Vom Endt D, Kijne JW, Memelink J (2002) Transcription factors controlling plant secondary metabolism: what regulates the regulators? Phytochemistry 61, 107-114.