%A Zhang Feng-xian, Wang Zhu-hao, Pan Wen-dou, Li Yu-jing, Mai Lang-tian, Sun Jian-quan and Ma Guang-en %T A Study on the Antitumor Plant Cephalotaxus oliveri Mast. %0 Journal Article %D 1978 %J J Integr Plant Biol %R %P -${article.jieShuYe} %V 20 %N 2 %U {https://www.jipb.net/CN/abstract/article_24696.shtml} %8 %X Three alkaloids: harringtonine, cephalotaxine and schelhammera alkaloid B were isolated from Cephalotaxus oliveri Mast. which is distributed in Guangdong Sheng. The inhibiting effect of harringtonine for sarcoma 180 in mice was 42.3% at a dosage of 1 mg/kg. It showed high activity against the acute nonlymphoblastic leukemia in clinical experiments. A pretty high yield of 1.3/10000 antileukemic ingredient harring- tonine was extracted from the plant and the resources of C. oliveri Mast. in China are abundant, so that this plant is a good material to produce harringtonine.