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J Integr Plant Biol, 55 (1): 5-6, Research Article
The Ever Expanding Role of Ubiquitin and SUMO in Plant Biology
Giovanna Serino1* and Qi Xie2
1Special Issue Editor, "Charles Darwin" Department of Biology and Biotechnology, Sapienza Università di Roma, Piazzale Aldo Moro 5, 00185 Roma, Italy
2Special Issue Editor, Laboratory of Plant Molecular Signaling, Institute of Genetics and Developmental Biology, Chinese Academy of Sciences, Beijing 100101, China
*Corresponding author E-mail: giovanna.serino@uniroma1.it
Abstract

When it was discovered in the 1970s as a ubiquitous protein, ubiquitin, a 76-aminoacid peptide, had no assigned function. It was not until later that ubiquitin was found to be a necessary cofactor in a vital cellular process: the degradation of proteins. Work by Avram Hershko, Aaron Ciechanover, and Irwin Rose (for which they received the 2004 Nobel Prize in Chemistry) showed that the covalent attachment of ubiquitin provide proteins with a tag that dispatches them to the proteasome, the main cell degradation machinery.

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Published: 21 January 2013
© 2013 Institute of Botany, Chinese Academy of Sciences
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