J Integr Plant Biol ›› 2015, Vol. 57 ›› Issue (10): 810-818.DOI: 10.1111/jipb.12424

• •    下一篇

Arabidopsis SMALL ORGAN 4, a homolog of yeast NOP53, regulates cell proliferation rate during organ growth

Xiao-Ran Zhang1†, Zhixiang Qin1†, Xiao Zhang1,2 and Yuxin Hu1,3*   

  • 收稿日期:2015-05-30 接受日期:2015-08-23 出版日期:2015-08-27 发布日期:2015-08-27

Arabidopsis SMALL ORGAN 4, a homolog of yeast NOP53, regulates cell proliferation rate during organ growth

Xiao-Ran Zhang1†, Zhixiang Qin1†, Xiao Zhang1,2 and Yuxin Hu1,3*   

  1. 1Key Laboratory of Plant Molecular Physiology, Institute of Botany, the Chinese Academy of Sciences, Beijing, China
    2University of Chinese Academy of Sciences, Beijing, China
    3National Center for Plant Gene Research, Beijing, China
  • Received:2015-05-30 Accepted:2015-08-23 Online:2015-08-27 Published:2015-08-27
  • About author:†These authors contributed equally to this work.
    *Correspondence: E-mail: huyuxin@ibcas.ac.cn

摘要： Cell division is a fundamental cellular event that contributes to the overall organ size in plants. How cell division progression is strictly regulated remains largely elusive during plant organogenesis. Here, the Arabidopsis SMO4, a homologue of yeast NOP53, is shown to regulate cell division progression and thus the final organ size.

Abstract:

Cell proliferation is a fundamental event essential for plant organogenesis and contributes greatly to the final organ size. Although the control of cell proliferation in plants has been extensively studied, how the plant sets the cell number required for a single organ is largely elusive. Here, we describe the Arabidopsis SMALL ORGAN 4 (SMO4) that functions in the regulation of cell proliferation rate and thus final organ size. The smo4 mutant exhibits a reduced size of organs due to the decreased cell number, and further analysis reveals that such phenotype results from a retardation of the cell cycle progression during organ development. SMO4 encodes a homolog of NUCLEOLAR PROTEIN 53 (NOP53) in Saccharomyces cerevisiae and is expressed primarily in tissues undergoing cell proliferation. Nevertheless, further complementation tests show that SMO4 could not rescue the lethal defect of NOP53 mutant of S. cerevisiae. These results define SMO4 as an important regulator of cell proliferation during organ growth and suggest that SMO4 might have been evolutionarily divergent from NOP53.

 

Zhang XR, Qin Z, Zhang X, Hu Y (2015) Arabidopsis SMALL ORGAN 4, a homolog of yeast NOP53, regulates cell proliferation rate during organ growth. J Integr Plant Biol 57: 810–818 doi: 10.1111/jipb.12424

Key words: Arabidopsis, cell proliferation, NOP53, organ size, SMO4

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