J Integr Plant Biol ›› 2020, Vol. 62 ›› Issue (11): 1647-1652.DOI: 10.1111/jipb.12979

所属专题： Epigenetics

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  • 收稿日期:2020-05-30 接受日期:2020-06-07 出版日期:2020-11-01 发布日期:2020-06-09

RNA-directed DNA methylation has an important developmental function in Arabidopsis that is masked by the chromatin remodeler PICKLE

Rong Yang1†, Li He1†, Huan Huang1, Jian-Kang Zhu1,2, Rosa Lozano-Duran1 and Heng Zhang1,3 *   

  1. 1 Shanghai Center for Plant Stress Biology, Center for Excellence for Molecular Plant Sciences, the Chinese Academy of Sciences, Shanghai 201062, China
    2 Department of Horticulture and Landscape Architecture, Purdue University, West Lafayette, Indiana 47907, USA
    3 National Key Laboratory of Plant Molecular Genetics, Center for Excellence for Molecular Plant Sciences, the Chinese Academy of Sciences, Shanghai 200032, China

    †These authors contributed equally
    *Correspondence:
    Email: Heng Zhang (hengzhang@psc.ac.cn)
  • Received:2020-05-30 Accepted:2020-06-07 Online:2020-11-01 Published:2020-06-09

Abstract: In Arabidopsis, RNA‐directed DNA methylation (RdDM) is required for the maintenance of CHH methylation, and for de novo methylation in all (CG, CHG, and CHH) contexts, but no obvious effect of RdDM deficiency on plant development has been found to date. We show that the combination of mutations in the chromatin remodeler PKL and RdDM components results in developmental alterations, which appear in a SUPPRESSOR OF DRM1 DRM2 CMT3 (SDC)‐dependent manner.

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