Abstract:

A new glycoside, γ-pyranone-3-O-β-D-［6′-(4″-hydroxy-3″,5″-dimethyoxybenzoyl)］ glucopyranoside (erigeside D, 2), together with nine known compounds, viz., erigeside Ⅰ (1), erigeside A (3), erigeside B (4), erigeside Ⅱ (5), scopolin (6), icariside B2(7), blumenol C glucoside (8),(+)-syringaresinol- O-β-D-glucopyranoside (9) and scutellarein –7-O-β-D-glucuronide methyl ester (10), was isolated from Erigeron breviscapus (Vant.) Hand.-Mazz. Their structures were established on the basis of spectral evidence.According to the β-glucopyranosyl moiety in 7, the absolute configuration of 7 was determined by X ray crystallographic analysis. Compounds 7, 8 and 9 were isolated for the first time from this genus, and compound 6 was first obtained from this plant.

灯盏花中的糖苷

陈斌  李伯刚  张国林^*

(中国科学院成都生物研究所,成都,610041)

从灯盏花(Erigeron breviscapus (Vant.) Hand.-Mazz.)全株的乙醇提取物的正丁醇部分分得10个化合物,通过波谱方法鉴定为erigeside Ⅰ (1)、γ-吡喃酮-3-O-β-D-[6′-(4″-羟基-3″,5″-二甲氧基苯甲酰)-]-吡喃葡萄糖苷(eriges ide D, 2)、erigeside A (3)、erigeside B (4)、erigesi de Ⅱ (5)、 7-O-β-D-吡喃葡萄糖-6-甲氧基香豆素(6)、 icariside B2 (7)、 blumenol C 葡萄糖苷(8)、 (+) -丁香树酯醇 O-β-D-吡喃葡萄糖苷(9)和野黄芩苷甲酯(10).用X射线单晶衍射方法确定了化合物7的绝对构型.2是一个新化合物,7、8和9首次从该属植物分离得到,6首次从该种植物分离得到.  

关键词 菊科 灯盏花 γ-吡喃酮-3-O-β-D-[6 ′-(4″-羟基-3″,5″-二甲氧基苯甲酰)]-吡喃葡萄糖苷

*通讯作者 Email: zhanggl@cib.ac.cn

Key words: Compositae, Erigeron breviscapus, γ-pyranone-3-O-β-D-［6′-(4″-hydroxy-3″,5″-dimethyoxybenzoyl)］-glucopyranoside (erigeside D)