Abstract:

A phytochemical investigation of the bark of Erythrophleum fordii Oliv. furnished five compounds. One is a new triterpenoid, namely 20S, 24S-epoxy-23S, 25-dihydroxy-dammarane-3-one (1), and four are known, identified to be 20S , 25-epoxy-24R -hydroxydammarane-3-one (2), 20S, 24S -epoxydammarane-3b,25-diol (3), betulinic acid (4), morolic acid acetate (5). All the known compounds were isolated from the species for the first time. The structure of compound 1 was elucidated on the basis of spectroscopic analyses.

Key words: Erythrophleum fordii , triterpenoid, cytotoxic activities, KB cells, A2780 cells