Table of Content
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, Volume 61 Issue 12
Cover Caption: Most of the epigenetic regulations occur within nucleus. Whether and how nucleo-cytoplasmic partitioning participates in chromatin regulation is largely unknown. In this issue, Zhu et al. (1243-1254) identified XPO1A as an anti-silencing factor through preventing DNA hypermethylation. XPO1A affects DNA methylation by guiding the nucleo-cytoplasm partitioning of histone deacetylase HDA6, thereby connecting the regulation of DNA methylation and transcriptional gene silencing with nucleo-cytoplasmic trafficking. [Detail] ...For Selected: Toggle Thumbnails
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