Abstract: In the present paper, using photo-microscopic method, the xeromorphism of some important xerophytes growing in south-east edge of Tungeli desert were determined. The xerophytes appeared to be different from mesophytes at common characteristics, lower in ratio between superficial area and mesophyll tissue volume and higher in ratio between palisade tissue and parenehyma. The xerophytes may be divided into two major groups; selerophylous xerophytes are characterized by a lot of small stomata, a large number of epidermal hair and developed conducting tissue and succulent xerophytes are characterized by a few of big stomata, thickness cuticle and developed water storage tissue. The role of xeromorphism in drought-resistance was also discussed.