Abstract: Eleven compounds were isolated from the leaves and bark of Podocarpus fleuryi Hickle (Podocarpaceae) for the first time. They were identified as palmitic acid (1), sugiol (2), β-sitosterol (3) nagilactone A(4), nagilactone B(5), isoginkgetin (6), β- sitosteryl stearate(7) 3β, 5α-dihydroxy-6-stigmastanone (8), 5α-hydroxy-6-stigmasta. none-3β-palmitate (9), daucosterol (10), and syringin (11) by means of spectral analysis, comparison of physico-chemical data, and through chemical methods. 9 was a new compound. 4 and 5 showed stronger cytotoxic activity.

Key words: Podocarpus fleuryi, Nagilactone A and B, 5α-hydroxy-6-stigmastanone-3β-palmitate