J Integr Plant Biol. ›› 2018, Vol. 60 ›› Issue (9): 827-840.DOI: 10.1111/jipb.12672

• Invited Expert Reviews • Previous Articles     Next Articles

The crossroads of receptor-mediated signaling and endocytosis in plants

Lucas Alves Neubus Claus1,2, Daniel V. Savatin1,2 and Eugenia Russinova1,2*   

  1. 1Department of Plant Biotechnology and Bioinformatics, Ghent University, 9052 Ghent, Belgium
    2Center for Plant Systems Biology, VIB, 9052 Ghent, Belgium


    Email: Eugenia Russinova (eurus@psb.vib-ugent.be)
  • Received:2018-02-27 Accepted:2018-06-05 Online:2018-06-07 Published:2018-09-01


Plants deploy numerous plasma membrane receptors to sense and rapidly react to environmental changes. Correct localization and adequate protein levels of the cell-surface receptors are critical for signaling activation and modulation of plant development and defense against pathogens. After ligand binding, receptors are internalized for degradation and signaling attenuation. However, one emerging notion is that the ligand-induced endocytosis of receptor complexes is important for the signal duration, amplitude, and specificity. Recently, mutants of major endocytosis players, including clathrin and dynamin, have been shown to display defects in activation of a subset of signal transduction pathways, implying that signaling in plants might not be solely restricted to the plasma membrane. Here, we summarize the up-to-date knowledge of receptor complex endocytosis and its effect on the signaling outcome, in the context of plant development and immunity.

Editorial Office, Journal of Integrative Plant Biology, Institute of Botany, CAS
No. 20 Nanxincun, Xiangshan, Beijing 100093, China
Tel: +86 10 6283 6133 Fax: +86 10 8259 2636 E-mail: jipb@ibcas.ac.cn
Copyright © 2022 by the Institute of Botany, the Chinese Academy of Sciences
Online ISSN: 1744-7909 Print ISSN: 1672-9072 CN: 11-5067/Q