Study on the Triterpenoids of Tripterygium  regeli

Abstract

Abstract: Ten triterpenoids were isolated from the ethanol extract of the roots of Tripteryglum regeli collected from Jilin Province, north-eastern China. They were identified as wilforlide A(1), wilforlide B(2), regelide (3) 3β-hydroxy-olean-ll,13(18)-diene (4), orthosphenic acid (5), salaspermic acid (6), 3-epikatonic acid(7), maytenfolic acid (8), 3β-acetyl-oleanolic acid (9), and celastrol (19), by spectroscopic analyses and chemical correlations. Compound 3—10 were isolated from T. regeli for the first time, among them regelide 3 was a new comound and its structure was elucidated to be 3-keto-22α-hydroxy-olean-ll,13(18)-dien-29-oic acid(29, 22α)-lactone. 3-epikatonic acid(7)showed obvious spermicidal effect, while cealstrol (10)revealed significant immunosuppressive activity.

Key words: Tripterygium regeli, Triterpenoid, Regelide

Shen Jian-hua and Zhou Bing-nan. Study on the Triterpenoids of Tripterygium regeli[J]. J Integr Plant Biol., 1992, 34(6): -.

[1]	Jinting Li and Zhenghai Hu. Accumulation and Dynamic Trends of Triterpenoid Saponin in Vegetative Organs of Achyranthus bidentata [J]. J Integr Plant Biol., 2009, 51(2): 122-129.
[2]	Xu-Min Zhu, Ping Xie, Ying-Tong Di, Shu-Lin Peng, Li-Sheng Ding and Ming-Kui Wang. Two New Triterpenoid Saponins from Gymnema sylvestre [J]. J Integr Plant Biol., 2008, 50(5): 589-592.
[3]	Dong-Mei Zhang, Li-Li Wang, Jia Li and Li-Hong Hu. Two New Coumarins from Fraxinus chinensis Rexb. [J]. J Integr Plant Biol., 2007, 49(2): -.
[4]	Gui-Yan Liu, Shuang-Cheng Ma, Jian Zheng, Ji Zhang and Rui-Chao Lin. Two New Triterpenoid Saponins from Akebia quinata (Thunb.) Decne. [J]. J Integr Plant Biol., 2007, 49(2): -.
[5]	Tun-Hai Xu, Ya-Juan Xu, Dong Han, Hong-Feng Zhao, Sheng-Xu Xie and Dong-Ming Xu. Triterpenoid Saponins from Pulsatilla cernua (Thunb.) [J]. J Integr Plant Biol., 2007, 49(2): -.
[6]	Xiang-Zhong Huang, Yue Liu, Shi-Shan Yu, You-Cai Hu and Jing Qu. Triterpenoids from the Roots of Craibiodendron henryi W. W. Smith [J]. J Integr Plant Biol., 2007, 49(11): 1615-1618.
[7]	Gao-Qiang LIU and Ke-Chang ZHANG. Mechanisms of the Anticancer Action of Ganoderma lucidum (Leyss. Ex Fr.) Karst.: A New Understanding [J]. J Integr Plant Biol., 2005, 47(2): -.
[8]	Fan ZHANG, Tie-Jun FU, Shu-Lin PENG, Zhong-Rong LIU and Li-Sheng DING. Two New Triterpenoids from the Roots of Sanguisorba officinalis L. [J]. J Integr Plant Biol., 2005, 47(2): -.
[9]	XIANG Ying, YANG Sheng-Ping, ZHAN Zha-Jun, YUE Jian-Min. Terpenoids and Phenols from Taiwania flousiana [J]. J Integr Plant Biol., 2004, 46(8): 1002-1008.
[10]	LI Nan, YU Fang, YU Shi-Shan. Triterpenoids from Erythrophleum fordii [J]. J Integr Plant Biol., 2004, 46(3): 371-374.
[11]	WANG Huan, ZHANG Xiao-Feng, YANG Shu-Min, LUO Xiao-Dong. A New Triterpenoid from Amoora dasyclada [J]. J Integr Plant Biol., 2004, 46(10): 1256-1260.
[12]	ZHU Wei Ming, SHEN Yue Mao, HONG Xin, ZUO Guo Ying,YANG Xiao Sheng, HAO Xiao Jiang . Triterpenoids from the Dai Medicinal Plant Winchia calophylla [J]. J Integr Plant Biol., 2002, 44(3): 354-358.
[13]	ZHANG Yong-Hong. A New Triterpenoid Saponin from Rhaponticum uniflorum (Compositae) [J]. J Integr Plant Biol., 2002, 44(3): 359-361.
[14]	DENG Ye, PENG Shu-Lin, ZHANG Xiao-Rong, DING Li-Sheng, WANG Ming-Kui. Triterpenoids from Rubus buergeri [J]. J Integr Plant Biol., 2001, 43(6): 644-646.
[15]	MIAO Zhen-Chun, FENG Rui, ZHOU Yong-Xin, WEI Feng. Chemical Structure and NMR of a New Saponin from Dipsacus japonicus (Dipsacaceae) [J]. J Integr Plant Biol., 2000, 42(4): 421-426.

Study on the Triterpenoids of Tripterygium regeli

PDF

Knowledge

Abstract

Cite this article

share this article

References

Related Articles 15

Recommended Articles

Metrics

Comments