J Integr Plant Biol board

Dr. Zhaojiang Guo

Professor
State Key Laboratory of Vegetable Biobreeding, Department of Plant Protection, Institute of Vegetables and Flowers, Chinese Academy of Agricultural Sciences, Beijing 100081, China
E-mail: guozhaojiang@caas.cn
Website: https://ivf.caas.cn/en/PEOPLE/Professor/6a8c48f3bc6e4547af6d99ee85c3d42e.htm
Area of expertise: Xenobiotic resistance, insect-plant/microbe interaction, insect-resistant crop breeding, gene regulation, horizontal gene transfer, RNAi-based pest control

Speciality Area

Plant Biotic Interactions

Selected Publications:

Hu Y, Gong C, Yang Z, Han H, Tian T, Yang X, Xie W, Wang S, Wu Q, Zhou X, Turlings TCJ, Guo Z, Zhang Y. (2025). Functional divergence of plant-derived thaumatin-like protein genes in two closely related whitefly species. Adv. Sci. (Weinh). 12: e2502193.

Su Q, Yang F, Hu Y, Peng Z, Huang T, Tong H, Zhang R, Yang Y, Zhou Z, Liang P, Zhu L, Wu Q, Zhang Y, Guo Z. (2025). Flavonoids enhance tomato plant resistance to whitefly by interfering with the expression of a salivary effector. Plant Physiol. 197: kiaf101.

Sun D, Xu Q, Guo L, Bai Y, Shentu X, Yu X, Crickmore N, Zhou X, Bravo A, Soberón M, Zhang Y, Guo Z. (2024). The role of GPI-anchored membrane-bound alkaline phosphatase in the mode of action of Bt Cry1A toxins in the diamondback moth. Fundam Res. 5: 674-682.

Guo Z, Zhu L, Cheng Z, Dong L, Guo L, Bai Y, Wu Q, Wang S, Yang X, Xie W, Crickmore N, Zhou X, Lafont R, Zhang Y. (2024). A midgut transcriptional regulatory loop favors an insect host to withstand a bacterial pathogen. Innovation (Camb). 5: 100675.

Gong C, Guo Z, Hu Y, Yang Z, Xia J, Yang X, Xie W, Wang S, Wu Q, Ye W, Zhou X, Turlings TCJ, Zhang Y. (2024). A horizontally transferred plant fatty acid desaturase gene steers whitefly reproduction. Adv. Sci. (Weinh). 11: e2306653.

Guo Z, Bai Y, Zhang X, Guo L, Zhu L, Sun D, Sun K, Xu X, Yang X, Xie W, Wang S, Wu Q, Crickmore N, Zhou X, Zhang Y. (2024). RNA m⁶A methylation suppresses insect juvenile hormone degradation to minimize fitness costs in response to a pathogenic attack. Adv. Sci. (Weinh). 11: e2307650.

Yang Z, Guo Z, Gong C, Xia J, Hu Y, Zhong J, Yang X, Xie W, Wang S, Wu Q, Ye W, Liu B, Zhou X, Turlings TCJ, Zhang Y. (2024). Two horizontally acquired bacterial genes steer the exceptionally efficient and flexible nitrogenous waste cycling in whiteflies. Sci. Adv. 10: eadi3105.

Guo Z, Guo L, Bai Y, Kang S, Sun D, Qin J, Ye F, Wang S, Wu Q, Xie W, Yang X, Crickmore N, Zhou X, Zhang Y. (2023). Retrotransposon-mediated evolutionary rewiring of a pathogen response orchestrates a resistance phenotype in an insect host. Proc. Natl. Acad. Sci. USA 120: e2300439120.

Guo Z, Guo L, Qin J, Ye F, Sun D, Wu Q, Wang S, Crickmore N, Zhou X, Bravo A, Soberón M, Zhang Y. (2022). A single transcription factor facilitates an insect host combating Bacillus thuringiensis infection while maintaining fitness. Nat. Commun. 13: 6024.

Sun D, Zhu L, Guo L, Wang S, Wu Q, Crickmore N, Zhou X, Bravo A, Soberón M, Guo Z, Zhang Y. (2022). A versatile contribution of both aminopeptidases N and ABC transporters to Bt Cry1Ac toxicity in the diamondback moth. BMC Biol. 20: 33.

Guo L, Cheng Z, Qin J, Sun D, Wang S, Wu Q, Crickmore N, Zhou X, Bravo A, Soberón M, Guo Z, Zhang Y. (2022). MAPK-mediated transcription factor GATAd contributes to Cry1Ac resistance in diamondback moth by reducing PxmALP expression. PLoS Genet. 18: e1010037.

Xia J, Guo Z, Yang Z, Han H, Wang S, Xu H, Yang X, Yang F, Wu Q, Xie W, Zhou X, Dermauw W, Turlings TCJ, Zhang Y. (2021). Whitefly hijacks a plant detoxification gene that neutralizes plant toxins. Cell 184: 3588.

Guo Z, Kang S, Wu Q, Wang S, Crickmore N, Zhou X, Bravo A, Soberón M, Zhang Y. (2021). The regulation landscape of MAPK signaling cascade for thwarting Bacillus thuringiensis infection in an insect host. PLoS Pathog. 17: e1009917.

Guo Z, Kang S, Sun D, Gong L, Zhou J, Qin J, Guo L, Zhu L, Bai Y, Ye F, Wu Q, Wang S, Crickmore N, Zhou X, Zhang Y. (2020). MAPK-dependent hormonal signaling plasticity contributes to overcoming Bacillus thuringiensis toxin action in an insect host. Nat Commun. 11: 3003.

Guo Z, Kang S, Chen D, Wu Q, Wang S, Xie W, Zhu X, Baxter SW, Zhou X, Jurat-Fuentes JL, Zhang Y. (2015). MAPK signaling pathway alters expression of midgut ALP and ABCC genes and causes resistance to Bacillus thuringiensis Cry1Ac toxin in diamondback moth. PLoS Genet. 11: e1005124.

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