J Integr Plant Biol. ›› 2010, Vol. 52 ›› Issue (1): 98-111.DOI: 10.1111/j.1744-7909.2010.00905.x

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Flavonoids: New roles for old molecules

Charles S. Buer*, Nijat Imin and Michael A. Djordjevic   

  1. Genomic Interactions Group, ARC Centre of Excellence for Integrative Legume Research, Research School of Biology, College of Medicine, Biology, and Environment, The Australian National University, Canberra ACT 2601, Australia
  • Received:2009-10-14 Accepted:2009-10-25 Published:2010-01-01
  • About author:*Author for correspondence Tel: +61 2 6125 3087; Fax: +61 2 6125 8525; Email: charles.buer@anu.edu.au doi: 10.1111/j.1744-7909.2010.00905.x


Flavonoids are ubiquitous in the plant kingdom and have many diverse functions including defense, UV protection, auxin transport inhibition, allelopathy, and flower coloring. Interestingly, these compounds also have considerable biological activity in plant, animal and bacterial systems – such broad activity is accomplished by few compounds. Yet, for all the research over the last three decades, many of the cellular targets of these secondary metabolites are unknown. The many mutants available in model plant species such as Arabidopsis thaliana and Medicago truncatula are enabling the intricacies of the physiology of these compounds to be deduced. In the present review, we cover recent advances in flavonoid research, discuss deficiencies in our understanding of the physiological processes, and suggest approaches to identify the cellular targets of flavonoids.

Buer CS, Imin N, Djordjevic MA (2010) Flavonoids: new roles for old molecules. J. Integr. Plant Biol. 52(1), 98–111.

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