J Integr Plant Biol. ›› 2022, Vol. 64 ›› Issue (11): 2199-2210.DOI: 10.1111/jipb.13358

• Plant Biotic Interactions • Previous Articles     Next Articles

The Phytophthora effector Avh94 manipulates host jasmonic acid signaling to promote infection

Yao Zhao1†, Bo Yang1,2†, Huawei Xu1, Jinbin Wu1, Zhiyang Xu1 and Yuanchao Wang1*   

  1. 1 Department of Plant Pathology, Nanjing Agricultural University, Nanjing 210095, China
    2 College of Grassland Science, Nanjing Agricultural University, Nanjing 210095, China

    These authors contributed equally to this work.
    * Correspondence: Yuanchao Wang (wangyc@njau.edu.cn)
  • Received:2022-05-02 Accepted:2022-09-02 Online:2022-09-06 Published:2022-11-01


The oomycete pathogen Phytophthora sojae is a causal agent of soybean root rot. Upon colonization of soybeans, P. sojae secretes various RXLR effectors to suppress host immune responses, supporting successful infection. Previous research has demonstrated that the RXLR effector Avh94 functions as a virulence effector, but the molecular mechanism underlying its role in virulence remains unknown. Here, we demonstrate that Avh94 overexpression in plants and pathogens promotes Phytophthora infection. Avh94 interacts with soybean JAZ1/2, which is a repressor of jasmonic acid (JA) signaling. Avh94 stabilizes JAZ1/2 to inhibit JA signaling and silencing of JAZ1/2 enhances soybean resistance against P. sojae. Moreover, P. sojae lines overexpressing Avh94 inhibit JA signaling. Furthermore, exogenous application of methyl jasmonate improves plant resistance to Phytophthora. Taken together, these findings suggest that P. sojae employs an RXLR effector to hijack JA signaling and thereby promote infection.

Editorial Office, Journal of Integrative Plant Biology, Institute of Botany, CAS
No. 20 Nanxincun, Xiangshan, Beijing 100093, China
Tel: +86 10 6283 6133 Fax: +86 10 8259 2636 E-mail: jipb@ibcas.ac.cn
Copyright © 2022 by the Institute of Botany, the Chinese Academy of Sciences
Online ISSN: 1744-7909 Print ISSN: 1672-9072 CN: 11-5067/Q