J Integr Plant Biol.
• Brief Communications •
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Optimizations of Cas12a- and Cas12i-based adenine base editors for efficient precision editing in the plant genome
Xiaoshuang Liu1†, Shan Jin1,2†, Zhi Xiao1,2†, Chong Ma1,2, Qing Wang1,3, Huanhuan Wang1, Ruohan Zhou1,2, Dongfang Gu2, Rongfang Xu2, Ruiying Qin2, Juan Li2* and Pengcheng Wei1,4*
- 1. College of Agronomy, Anhui Agricultural University, Hefei 230036, China
2. Bio‐breeding Laboratory of Anhui Province, Rice Research Institute, Anhui Academy of Agricultural Sciences, Hefei 230036, China
3. Wuxi Japonica Rice Industry Technology Center, State Key Laboratory of Rice Biology and Breeding & Wuxi Hupper Biological Seed Industry Technology Institute Ltd, Wuxi 214000, China
4. Research Centre for Biological Breeding Technology, Advance Academy, Anhui Agricultural University, Hefei 230036, China
†These authors contributed equally to this paper.
*Correspondences: Pengcheng Wei (weipengcheng@ahau.edu.cn, Dr. Wei is fully responsible for the distribution of all materials associated with this article); Juan Li (lijuan@aaas.org.cn)
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Received:2025-11-25
Accepted:2026-01-18
Online:2026-02-09
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Supported by:This work was supported by the Agriculture Science and Technology Major Project, the Science and Technology Major Project of Anhui Province (No. 202423110050063, No. 202423m10050002 and No. 2023n06020020), the Natural Science Foundation of China (No. 32300343, No. 32572441 and No. 32570484), and Yangtze River Delta Science and Technology Innovation Community Joint Research (Basic Research) Project (No. 2024CSJZN01100).
