J Integr Plant Biol.
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Base editing in rice using nuclease‐deactivated CRISPR/Cas‐SF01
Meng Jia1†, Yangqing Xie1†, Chuang Wei1†, Hongzhi Wang2†, Li Xue1, Chunyu Zou1,Jian-Kang Zhu1,3* and Mugui Wang1*
- 1. Key Laboratory of Gene Editing Technologies (Hainan), Ministry of Agriculture and Rural Affairs, National Nanfan Research Institute, and Institute of Crop Sciences, Chinese Academy of Agricultural Sciences, Sanya 572024, China
2. Special Orphan Crops Research Center of the Loess Plateau, Ministry of Agriculture and Rural Affairs, College of Agriculture, Shanxi Agricultural University, Taigu 030801, China
3. Institute of Advanced Biotechnology and School of Medicine, Southern University of Science and Technology, Shenzhen 518055, China
†These authors contributed equally to this work.
*Correspondences: Mugui Wang (wangmugui@caas.cn, Dr. Wang is fully responsible for the distribution of all materials associated with this article); Jian-Kang Zhu (zhujk@sustech.edu.cn)
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Received:2025-11-30
Accepted:2026-03-27
Online:2026-04-14
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Supported by:This study was supported by the Agriculture Science and Technology
Major Project, and Nanfan special project of CAAS (YBXM2514) to
M.W.; National Key R&D Program of China (2021YFA1300404),
Guangdong S&T Program (2024B1111130001), Shenzhen Science
and Technology Program (KQTD20240729102038044), and National
Natural Science Foundation of China (32188102) to J.‐K.Z.