J Integr Plant Biol. ›› 2020, Vol. 62 ›› Issue (1): 2-24.DOI: 10.1111/jipb.12898

Special Issue: Plant-biotic interaction

• Invited Expert Reviews For Plant Research Progress •     Next Articles

Plant immune signaling: Advancing on two frontiers

Wei Wang1, Baomin Feng1, Jian-Min Zhou2* and Dingzhong Tang1*   

  1. 1State Key Laboratory of Ecological Control of Fujian‐Taiwan Crop Pests, Key Laboratory of Ministry of Education for Genetics, Breeding and Multiple Utilization of Crops, Plant Immunity Center, Fujian Agriculture and Forestry University, Fuzhou 350002, China
    2The State Key Laboratory of Plant Genomics, Institute of Genetics and Developmental Biology, Chinese Academy of Sciences, Beijing 100101, China

    Email: Jianmin Zhou (jmzhou@genetics.ac.cn); Dingzhong Tang (dztang@genetics.ac.cn, Dr Tang is fully responsible for the distribution of all materials associated with this article)
  • Received:2019-11-21 Accepted:2019-12-16 Online:2019-12-17 Published:2020-01-01


Plants have evolved multiple defense strategies to cope with pathogens, among which plant immune signaling that relies on cell‐surface localized and intracellular receptors takes fundamental roles. Exciting breakthroughs were made recently on the signaling mechanisms of pattern recognition receptors (PRRs) and intracellular nucleotide‐binding site (NBS) and leucine‐rich repeat (LRR) domain receptors (NLRs). This review summarizes the current view of PRRs activation, emphasizing the most recent discoveries about PRRs’ dynamic regulation and signaling mechanisms directly leading to downstream molecular events including mitogen‐activated protein kinase (MAPK) activation and calcium (Ca2+) burst. Plants also have evolved intracellular NLRs to perceive the presence of specific pathogen effectors and trigger more robust immune responses. We also discuss the current understanding of the mechanisms of NLR activation, which has been greatly advanced by recent breakthroughs including structures of the first full‐length plant NLR complex, findings of NLR sensor‐helper pairs and novel biochemical activity of Toll/interleukin‐1 receptor (TIR) domain.

Editorial Office, Journal of Integrative Plant Biology, Institute of Botany, CAS
No. 20 Nanxincun, Xiangshan, Beijing 100093, China
Tel: +86 10 6283 6133 Fax: +86 10 8259 2636 E-mail: jipb@ibcas.ac.cn
Copyright © 2022 by the Institute of Botany, the Chinese Academy of Sciences
Online ISSN: 1744-7909 Print ISSN: 1672-9072 CN: 11-5067/Q