J Integr Plant Biol. ›› 2022, Vol. 64 ›› Issue (2): 431-448.DOI: 10.1111/jipb.13182

• Invited Expert Reviews • Previous Articles     Next Articles

TRAF proteins as key regulators of plant development and stress responses

Hua Qi1,2, Fan‐Nv Xia3, Shi Xiao2,3* and Juan Li4*   

  1. State Key Laboratory for Conservation and Utilization of Subtropical Agro‐Bioresources, College of Plant Protection, South China Agricultural University, Guangzhou 510642, China
    2 Guangdong Laboratory for Lingnan Modern Agriculture, Guangzhou 510642, China
    3 State Key Laboratory of Biocontrol, Guangdong Provincial Key Laboratory of Plant Resources, School of Life Sciences, Sun Yat‐sen University, Guangzhou 510275, China
    4 College of Agronomy, Hunan Agricultural University, Changsha 410128, China

    *Correspondences: Juan Li (adalee619@163.com, Dr. Li is responsible for the distribution of the materials associated with this article); Shi Xiao (xiaoshi3@mail.sysu.edu.cn)
  • Received:2021-09-01 Accepted:2021-10-18 Online:2021-10-21 Published:2022-02-01

Abstract: Tumor necrosis factor receptor-associated factor (TRAF) proteins are conserved in higher eukaryotes and play key roles in transducing cellular signals across different organelles. They are characterized by their C-terminal region (TRAF-C domain) containing seven to eight anti-parallel β-sheets, also known as the meprin and TRAF-C homology (MATH) domain. Over the past few decades, significant progress has been made toward understanding the diverse roles of TRAF proteins in mammals and plants. Compared to other eukaryotic species, the Arabidopsis thaliana and rice (Oryza sativa) genomes encode many more TRAF/MATH domain-containing proteins; these plant proteins cluster into five classes: TRAF/MATH-only, MATH-BPM, MATH-UBP (ubiquitin protease), Seven in absentia (SINA), and MATH-Filament and MATH-PEARLI-4 proteins, suggesting parallel evolution of TRAF proteins in plants. Increasing evidence now indicates that plant TRAF proteins form central signaling networks essential for multiple biological processes, such as vegetative and reproductive development, autophagosome formation, plant immunity, symbiosis, phytohormone signaling, and abiotic stress responses. Here, we summarize recent advances and highlight future prospects for understanding on the molecular mechanisms by which TRAF proteins act in plant development and stress responses.

Editorial Office, Journal of Integrative Plant Biology, Institute of Botany, CAS
No. 20 Nanxincun, Xiangshan, Beijing 100093, China
Tel: +86 10 6283 6133 Fax: +86 10 8259 2636 E-mail: jipb@ibcas.ac.cn
Copyright © 2022 by the Institute of Botany, the Chinese Academy of Sciences
Online ISSN: 1744-7909 Print ISSN: 1672-9072 CN: 11-5067/Q