J Integr Plant Biol. ›› 2006, Vol. 48 ›› Issue (4): -.
• Research Articles •
Zi-Chun Xiang, Yan Jiang and Shun-Xing Guo
In order to isolate anti-human immunodeficiency virus (HIV) agents from natural products, 97 ethanolic extracts of 90 fungi were tested for their inhibitory activity on HIV-1. Most of the extracts tested were relatively non-toxic to human lymphocytic MT-4 cells, but extracts of some fungi exhibited potent anti-HIV activity in an in vitro 3-(4,5-dimethyl-2 thiazoyl)-2,5-diphenyl-2H-tetrazolium bromide assay with a selectivity index greater than 3. Most fungi were isolated from Dendrobium sp. and Taxus sp.(Author for correspondence.Tel: +86 10 6302 4898; Fax: +86 10 6302 4898; E-mail: Jiangyan03@263.net)
3-(4,5-dimethyl-2 thiazoyl)-2,5-diphenyl-2H-tetrazolium bromide method,
antihuman immunode ficiency virus.
Zi-Chun Xiang, Yan Jiang and Shun-Xing Guo. Screening of Fungi from Chinese Medical Plants for Anti-Human Immunodeficiency Virus Type 1 Activity[J]. J Integr Plant Biol., 2006, 48(4): -.
Add to citation manager EndNote|Ris|BibTeX