J Integr Plant Biol. ›› 2019, Vol. 61 ›› Issue (1): 7-11.DOI: 10.1111/jipb.12748

• Letter to the Editor • Previous Articles     Next Articles

Acquisition of deleterious mutations during potato polyploidization

Qun Lian1,2†, Die Tang1†, Zhiyan Bai1†, Jianjian Qi2, Fei Lu3,4, Sanwen Huang1 and Chunzhi Zhang1*   

  1. 1Genome Analysis Laboratory of the Ministry of Agriculture, Agricultural Genomics Institute, the Chinese Academy of Agricultural Sciences, Shenzhen 518124, China
    2Inner Mongolia Potato Engineering and Technology Research Centre, Inner Mongolia University, Hohhot 010021, China
    3The State Key Laboratory of Plant Cell and Chromosome Engineering, Institute of Genetics and Developmental Biology, the Chinese Academy of Sciences, Beijing 100101, China
    4CAS-JIC Centre of Excellence for Plant and Microbial Science (CEPAMS), Shanghai Institutes for Biological Sciences, the Chinese Academy of Sciences, Shanghai 200032, China

    ?These authors contributed equally to the work.

    Email: Chunzhi Zhang (zhangchunzhi01@caas.cn)
  • Received:2018-08-29 Accepted:2018-11-12 Online:2018-11-26 Published:2019-01-01

Abstract: Potatoes (Solanum tuberosum L.) represent an important tuber crop, worldwide. During its prolonged clonal propagation, numerous deleterious mutations have accumulated in the potato genome, leading to severe inbreeding depression; however, the shaping of this mutation burden during polyploidization and improvement is largely unknown. Here, we sequenced 20 diploid landraces of the Stenotomum group, eight tetraploid landraces, and 20 tetraploid modern cultivars, to analyze variations in their deleterious mutations. We show that deleterious mutations accumulated rapidly during the polyploidization of tetraploid potatoes. This study provides a foundation for future potato improvement.

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