J Integr Plant Biol. ›› 2022, Vol. 64 ›› Issue (4): 836-842.DOI: 10.1111/jipb.13241
• Breakthrough Report •
Fan Xu†, Li Huang†, Junyao Wang, Caixia Ma, Yingqing Tan, Fanlong Wang, Yanhua Fan and Ming Luo*
Verticillium wilt caused by Verticillium dahliae is a major disease of cotton. Acidic protein–lipopolysaccharide complexes are thought to be the toxins responsible for its symptoms. Here, we determined that the sphingolipid biosynthesis inhibitor fumonisin B1 (FB1) acts as a toxin and phenocopies the symptoms induced by V. dahliae. Knocking out genes required for FB1 biosynthesis reduced V. dahliae pathogenicity. Moreover, we showed that overexpression of a FB1 and V. dahliae both downregulated gene, GhIQD10, enhanced verticillium wilt resistance by promoting the expression of brassinosteroid and anti-pathogen genes. Our results provide a new strategy for preventing verticillium wilt in cotton.
Fan Xu, Li Huang, Junyao Wang, Caixia Ma, Yingqing Tan, Fanlong Wang, Yanhua Fan and Ming Luo. Sphingolipid synthesis inhibitor fumonisin B1 causes verticillium wilt in cotton[J]. J Integr Plant Biol., 2022, 64(4): 836-842.
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