J Integr Plant Biol. ›› 2006, Vol. 48 ›› Issue (4): -.DOI: 10.1111/j.1744-7909.2006.00226.x

• Research Articles •    

Two New Cytotoxic Sesquiterpenoids from Eupatorium lindleyanum DC.

Jun Huo, Sheng-Ping Yang, Jian Ding and Jian-Min Yue   

Abstract: Two new sesquiterpenoid lactones, namely eupalinilides K and L, were isolated from Eupatorium lindleyanum DC. Their structures were determined by spectral methods, including 1D- and 2D-NMR spectra. Cytotoxic evaluation showed that eupalinilide L exhibited potent cytotoxicity against P-388 and A-549 tumor cell lines with IC50 values of 0.17 and 2.60 μmol/L, respectively.(Author for correspondence.E-mail: jmyue@mail.shcnc.ac.cn)

Key words: eupalinilides K and L, Eupatorium lindleyanum, sesquiterpenoid.

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