J Integr Plant Biol. ›› 2016, Vol. 58 ›› Issue (2): 106-118.DOI: 10.1111/jipb.12377

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Plant Mediator complex and its critical functions in transcription regulation

Yan Yang1, Ling Li1 and Li-Jia Qu1,2*   

  1. 1State Key Laboratory of Protein and Plant Gene Research, Peking-Tsinghua Center for Life Sciences, College of Life Sciences, Peking University, Beijing 100871, China
    2The National Plant Gene Research Center (Beijing), Beijing 100101, China
  • Received:2015-01-05 Accepted:2015-07-07 Published:2015-07-14
  • About author:*Correspondence: E-mail: qulj@pku.edu.cn


The Mediator complex is an important component of the eukaryotic transcriptional machinery. As an essential link between transcription factors and RNA polymerase II, the Mediator complex transduces diverse signals to genes involved in different pathways. The plant Mediator complex was recently purified and comprises conserved and specific subunits. It functions in concert with transcription factors to modulate various responses. In this review, we summarize the recent advances in understanding the plant Mediator complex and its diverse roles in plant growth, development, defense, non-coding RNA production, response to abiotic stresses, flowering, genomic stability and metabolic homeostasis. In addition, the transcription factors interacting with the Mediator complex are also highlighted.


Yang Y, Li L, Qu L-J (2016) Plant Mediator complex and its critical functions in transcription regulation. J Integr Plant Biol 58: 106–118 doi: 10.1111/jipb.12377

Key words: Mediator complex, transcription factors, transcription regulation

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