J Integr Plant Biol. ›› 2017, Vol. 59 ›› Issue (4): 230-233.DOI: 10.1111/jipb.12526

• Letters to the Editor •     Next Articles

Tonoplast targeting of VHA-a3 relies on a Rab5-mediated but Rab7-independent vacuolar trafficking route

Qiang-Nan Feng, Yan Zhang and Sha Li*   

  1. State Key Laboratory of Crop Biology, College of Life Sciences, Shandong Agricultural University, Tai'an, China
  • Received:2017-01-25 Accepted:2017-02-09 Published:2017-02-15
  • About author:*Correspondence: E-mail: Sha Li (shali@sdau.edu.cn)


Vacuolar trafficking routes and their regulators have recently drawn lots of attention in plant cell biology. A recent study reported the discovery of a plant-specific vacuolar trafficking route, i.e., a direct ER-to-vacuole route, through analysis of VHA-a3 subcellular targeting, a key component for the tonoplast V-ATPases. Our recent findings showed that VHA-a3 targets to the tonoplast through a Rab5-mediated but Rab7-independent pathway, shedding new lights on the unconventional vacuolar trafficking route in plant cells.

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