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, Volume 59 Issue 4Cover Caption: Similar to the transportation network in a city, the dynamic trafficking of membrane proteins is crucial for a cell to function properly. In this issue, Feng et al. (230-233) demonstrate that tonoplast associated V-ATPase is transported through a Rab5-mediated but Rab7- independent pathway, suggesting the presence of a non-conventional vacuolar trafficking route in plant cells.
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