J Integr Plant Biol. ›› 2021, Vol. 63 ›› Issue (2): 283-296.DOI: 10.1111/jipb.13032
• Invited Expert Review •
Junzhu Wang1,2, Meng Han1,2 and Yule Liu1,2*
Plant nucleotide‐binding, leucine‐rich repeat receptors (NLRs) perceive pathogen avirulence effectors and activate defense responses. Nucleotide‐binding, leucine‐rich repeat receptors are classified into coiled‐coil (CC)‐containing and Toll/interleukin‐1 receptor (TIR)‐containing NLRs. Recent advances suggest that NLR CC domains often function in signaling activation, especially for induction of cell death. In this review, we outline our current understanding of NLR CC domains, including their diversity/classification and structure, their roles in cell death induction, disease resistance, and interaction with other proteins. Furthermore, we provide possible directions for future work.
Junzhu Wang, Meng Han and Yule Liu. Diversity, structure and function of the coiled‐coil domains of plant NLR immune receptors[J]. J Integr Plant Biol., 2021, 63(2): 283-296.
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