J Integr Plant Biol.
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A novel Cas12b cytosine base editor enables efficient C-to-T base editing in the rice genome
Yulei Wei1,2†, Lin He2†, Jienan Han3†, Shengnan Ge2, Xueheyuan Wang2, Xinyu Liu2, Jie Deng2, Haiyang Zhang2, Xinyang Che2, Jianfeng Weng3*, Wujun Ma1* and Jingyu Xu1,2*
- 1. Crop Genome Editing Research Center, College of Agronomy, Qingdao Agricultural University, Qingdao 266109, China
2. Key Laboratory of Modern Agricultural Cultivation and Crop Germplasm Improvement of Heilongjiang Province, College of Agriculture, Heilongjiang Bayi Agricultural University, Daqing 163319, China
3. State Key Laboratory of Crop Gene Resources and Breeding, National Key Facility for Crop Gene Resources and Genetic Improvement, Institute of Crop Sciences, Chinese Academy of Agricultural Sciences, Beijing 100081, China
†These authors contributed equally to this work.
*Correspondences: Jingyu Xu (xujingyu218@outlook.com, Dr. Xu is fully responsible for the distribution of all materials associated with this article); Wujun Ma (wujun.ma@qau.edu.cn); Jianfeng Weng (wengjianfeng@caas.cn)
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Received:2025-11-30
Accepted:2026-06-29
Online:2026-07-19
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Supported by:This work was supported by the Agriculture Science and Technology Major Project (NK202201020312, NK202201020309), the Inner Mongolia Innovation Center of Biological Breeding Technology, the Central Public‐interest Scientific Institution Basal Research Fund (Y2026FZ15, S2026QZ14), and the Central Public‐interest Scientific Institution Basal Research Fund (No. Y2026GH11).
