J Integr Plant Biol. ›› 2001, Vol. 43 ›› Issue (6): 647-649.

• Research Articles • Previous Articles     Next Articles

Study of Sesquiterpene Alkaloids from Tripterygium wilfordii (IV)

LIN Sui, LI Yuan-Chao, NOBUKO Sakurai, GUO Shun-Min, DENG Fu-Xiao   

Abstract:

Two sesquiterpene alkaloids,wilforine and wilfordsuine were isolated from Tripterygium wilfordii Hook. f. Wilfordsuine was a new alkaloid. The structures of wilforine and wilfordsuine were elucidated on the basis of spectral data,especially 2D-NMR techniques (H'-'H COSY,H'-13C COSY, NOESY, COLOC methods).

雷公藤倍半萜生物碱的研究(IV)
林绥1 李援朝 樱井信子3 郭舜民1  邓福孝1

(1. 福建省医学科学研究所,福州350001;2. 中国科学院上海药物研究所,上海200031;3.Hoshi University, Tokyk 142, Japan)

摘要:从雷公藤 (Tripterygiumwilfordii Hook .f.)的根皮中分离到两个倍半萜生物碱Ⅰ和Ⅱ ,根据理化性质和波谱数据特别是 2D NMR技术 (1H 1HCOSY、1H 13 CCOSY、NOESY、COLOC)数据分析 ,鉴定Ⅰ为wilforine ,Ⅱ为一新的生物碱———雷公藤植碱 (wilfordsuine)。

关键词: 雷公藤;倍半萜生物碱;wilforine;雷公藤植碱

Key words: Tripterygium wilfordii , sesquiterpene alkaloids, wilforine, wilfordsuine

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