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J Integr Plant Biol, 2001, 43 (7): 760-765, Research Article
New Minor Cyclic Peptides from Brachystemma calycinum (in English) CHENG
Yong-Xian, ZHOU Jun and TAN Ning-Hua
doi:
Abstract

From the ethanol extract of the roots of Brachystemma calycinum D.Don, a Chinese folk herb, four new minor cyclic peptides namely brachystemin A, B, C and D (1-4) have been isolated. Their structures were established as cyclo (Pro¹-Phe-Leu-Ala¹-Thr-Pro²-Ala²-Gly)(1)、cyclo(Pro¹-Ala-Phe-Trp-Asp-Pro²-Leu-Gly)(2)、cyclo (Pro¹-Ile-Gly-Pro²-Val-Ala¹-Ala²-Tyr) (3) and cyclo (Pro-OMet-Trp-Ile-Gly-Ala-Leu-Asp) (T4) respectively by means of extensive spectral methods.

短瓣花中的微量新环肽成分
程永现 周俊*  谭宁华
(中国科学院昆明植物研究所植物化学开放实验室,昆明650204)

摘要:从中国民间草药短瓣花(Brachystemma calycinum D.Don)干燥根的乙醇提取物中分离得到4个新的微量环八肽,命名为短瓣花环肽A、B、C和D。经光谱分析鉴定,它们的结构分别为cyclo (Pro1-Phe-Leu-Ala1-Thr-Pro2-Ala2-Gly) (1)、cyclo (Pr o1-Ala-Phe-Trp-Asp-Pro2-Leu-Gly) (2)、cyclo (Pro1-Ile-Gly-Pro 2-Val-Ala1-Ala2-Tyr) (3)和cyclo (Pro-OMet-Trp-Ile-Gly-Ala-Leu- Asp) (4)。

关键词: 石竹科;短瓣花;环肽;短瓣花环肽A、B、C、D

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