Abstract: Sinenofuranal and sinenofuranol, two new sesquiterpenoids were isolated from the essential oil of Aquilaria sinensis (Lour.) Gilg. by flash column chromatography (silica gel) and Sephadex-20 column chromatography Based on preparation, spectra of derivative sinenofuranic acid (Ⅶ), the analysis of X-ray diffraction and spectra of sinenofuranol (Ⅱ), the structures of two sesquiterpenoids were elucidated as (Ⅰ) and (Ⅱ) in Fig. respectively Baimuxinal, baimuxinic acid, β-agarofuran, dihydro karanone were also isolated.

Key words: Aquilaria sinensis, Essential oil, Sinenofuranal, Amenofuranol, Sinenofuranic acid