Integrative Biology Journals
JIPB

J Integr Plant Biol. ›› 2022, Vol. 64 ›› Issue (11): 2029-2032.DOI: 10.1111/jipb.13352

• Brief Communications •     Next Articles

Base editing-mediated targeted evolution of ACCase for herbicide-resistant rice mutants

Hongzhi Wang1,2†, Yuxin He1,2†, Yingying Wang1,2†, Zuren Li3, Jiannan Hao1,2, Yijiao Song4, Mugui Wang1* and Jian‐Kang Zhu1,5,6*   

  1. 1 Shanghai Center for Plant Stress Biology and Center for Excellence in Molecular Plant Sciences, Chinese Academy of Sciences, Shanghai 201602, China
    2 University of Chinese Academy of Sciences, Beijing 100049, China
    3 Hunan Provincial Key Laboratory for Biology and Control of Weeds, Hunan Academy of Agricultural Sciences, Changsha 410125, China
    4 College of Life Sciences, Nanjing Agricultural University, Nanjing 210095, China
    5 Institute of Advanced Biotechnology and School of Life Sciences, Southern University of Science and Technology, Shenzhen 518055, China
    6 Center for Advanced Bioindustry Technologies, Chinese Academy of Agricultural Sciences, Beijing 100081, China

    † These authors contributed equally to this work.
    * Correspondences: Jian‐Kang Zhu (zhujk@sustech.edu.cn, Dr. Zhu is fully responsible for the distribution of the materials associated with this article); Mugui Wang (mgwang@cemps. ac.cn)
  • Received:2022-06-16 Accepted:2022-08-26 Online:2022-08-29 Published:2022-11-01

HTML

PDF

Cited

6

Abstract: Improved cytosine and adenine base editors and an efficient dual editor were applied in targeted evolution of ACETYL COA CARBOXYLASE in rice, resulting in the generation of dozens of herbicide-resistant mutations, at least three of which, W2125L, W2125Q and C2186H, have not been reported previously.

Editorial Office, Journal of Integrative Plant Biology, Institute of Botany, CAS
No. 20 Nanxincun, Xiangshan, Beijing 100093, China
Tel: +86 10 6283 6133 Fax: +86 10 8259 2636 E-mail: jipb@ibcas.ac.cn
Copyright © 2022 by the Institute of Botany, the Chinese Academy of Sciences
Online ISSN: 1744-7909 Print ISSN: 1672-9072 CN: 11-5067/Q
备案号：京ICP备16067583号-22