1. The State Key Laboratory of Plant Cell and Chromosome Engineering, Institute of Genetics and Developmental Biology, the Chinese cademy of Sciences, Beijing 100101, China; 2. University of the Chinese Academy of Sciences, Beijing 100049, China; 3. Beijing Institute of Genomics, Chinese Academy of Sciences, National Center for Bioinformation, Beijing 100101, China *Correspondence: Yongbiao Xue (ybxue@genetics.ac.cn)