Abstract:

A new monoterpene glycoside, hemiphroside C (1), along with seven known compounds were isolated from the whole plants of Hemiphragma heterophyllum Wall. By spectral evidence, the structure of the new compound was elucidated as (4S)-a-terpineol 8-O-b-D-xylopyranosyl-(1→6)-b-D-glucopyranoside. The known compounds were identified to be globularin (2), (2S, 3S, 4R, 9E)-1, 3, 4-trihydroxy-2-[(2''R)-hydroxytetracosanoylamino]-9-octadecene (3), b-amyrin (4), oleanolic acid (5), cinnamic acid (6), b-sitosterol (7) and daucosterol (8). All compounds except compound 2 were firstly isolated from H. heterophyllum.

Key words: Hemiphragma heterophyllum, a-terpineol, hemiphroside C, ceramide