Advances in research on plant CNGCs, the Ca2+-permeable channels

doi:10.1111/jipb.70385

J Integr Plant Biol.

• Review Article • Next Articles

Advances in research on plant CNGCs, the Ca²⁺-permeable channels

Yan-Qiu Tan^{1, 2}, Yang Yang^{1, 2} and Yong-Fei Wang^{1, 2*}

1. State Key Laboratory of Plant Trait Design, CAS Center for Excellence in Molecular Plant Sciences, Chinese Academy of Sciences, Shanghai 200032, China
2. University of Chinese Academy of Sciences, Shanghai 200032, China
*Correspondence: Yong‐Fei Wang (yfw@cemps.ac.cn)

Received:2026-07-10 Accepted:2026-08-23 Online:2026-09-07
Supported by:
This work was supported by the Strategic Priority Research Program of the Chinese Academy of Sciences (grant No. XDB1490000) and the Key Laboratory of Plant Carbon Capture of CAS (CNXT002 to Y.-F.W.), and was partially supported by the National Natural Science Foundation of China (32270279 and 32470332 to Y.-F.W., 32300253 and 32570343 to Y.-Q.T., and 32300214 to Y.Y.), the China Postdoctoral Science Foundation (2024M753231 to Y.Y.), and the Shanghai Post-doctoral Excellence Program (2024652 to Y.Y.).

Abstract

Abstract: Cyclic nucleotide-gated channels (CNGCs) in plants are the orthologs of cyclic nucleotide-gated (CNG) channels, which function as non-selective cation channels in olfactory and visual signal transduction in animals. In land plants, CNGCs form a large Ca²⁺-permeable cation channel family, and function in diverse biological processes, mainly including the uptake of cationic nutrients and toxic heavy metals from the soil, the transport, distribution, and homeostasis of these cations, and Ca²⁺ signaling in plants. Significant advances have been made in recent years, with new findings that have greatly expanded our understanding of plant CNGCs. This review summarizes the major progress over the past 5 years and discusses the open scientific questions that remain to be addressed.

Key words: Ca²⁺ channels, Ca²⁺ signaling, CNGCs, ion homeostasis, ion nutrients, plants

Yan-Qiu Tan, Yang Yang, Yong-Fei Wang. Advances in research on plant CNGCs, the Ca²⁺-permeable channels[J]. J Integr Plant Biol., DOI: 10.1111/jipb.70385.

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Advances in research on plant CNGCs, the Ca²⁺-permeable channels

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