J Integr Plant Biol. ›› 2014, Vol. 56 ›› Issue (8): 729-740.DOI: 10.1111/jipb.12196

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Plant pleiotropic drug resistance transporters: Transport mechanism, gene expression, and function

Mohammed Nuruzzaman1, Ru Zhang1, Hong-Zhe Cao1 and Zhi-Yong Luo1,2*   

  1. 1Molecular Biology Research Center, School of Life Sciences, Central South University, Changsha, China
    2State Key Laboratory of Medical Genetics, Xiangya School of Medicine, Central South University, Changsha, China
  • Received:2014-02-20 Accepted:2014-03-17 Published:2014-03-20
  • About author:*Correspondence: E-mail: luo_zhiyong@hotmail.com


Pleiotropic drug resistance (PDR) transporters belonging to the ABCG subfamily of ATP-binding cassette (ABC) transporters are identified only in fungi and plants. Members of this family are expressed in plants in response to various biotic and abiotic stresses and transport a diverse array of molecules across membranes. Although their detailed transport mechanism is largely unknown, they play important roles in detoxification processes, preventing water loss, transport of phytohormones, and secondary metabolites. This review provides insights into transport mechanisms of plant PDR transporters, their expression profiles, and multitude functions in plants.


Nuruzzaman M, Zhang R, Cao HZ, Luo ZY (2014) Plant pleiotropic drug resistance transporters: Transport mechanism, gene expression, and function. J Integr Plant Biol 56: 729–740. doi: 10.1111/jipb.12196

Key words: ABC transporters, expression pattern, plant defense, pleiotropic drug resistance, transport mechanism

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